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Could omeprazole cause my dog to lose appetite or feel full?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Male | unneutered | 1 year old | 55 lbs

Is omeprazole causing my dog to have no appetite? Our vet isn't open now. Could it make him feel full? He ate at 5 am but after his omeprazole this morning he wouldn't eat. Would reducing it to once a day be fine? To see if his appetite returns by tomorrow?

1 Answer

Most Helpful Answer

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Answered By Lauren Jones VMD

Veterinarian

Published on April 24th, 2017

Omeprazole is a powerful antacid that blocks acid production in the stomach to protect the gastrointestinal tract against ulcers. However, in occasional cases, it can cause a loss of appetite, vomiting or diarrhea. There is a chance that Spock may be feeling nauseous due to the omeprazole and is not eating due to nausea. Unfortunately, since I have not personally examined Spock, I am legally unable to provide you with precise dosing instructions and must instruct you to follow your vet's prescription. Be sure to call your vet first thing in the morning so that they can adjust Spocks antacid dosing or switch to a different medication. I hope that all goes well!

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