My dog has seizures. Can spaying help reduce their frequency?

Question

Our 4 yr old shepherd has been having seizures since she was 1 1/2. She's on pheno and zonisamide. She has seizures every 4 to 6 wks. She has been having cluster's also, usually 3 or 4 in a 24hr period. She hasn't yet been spayed. Do you think getting her spayed will help reduce the seizures? Pet's info: Dog | German Shepherd | Female | unspayed | 3 years and 5 months old | 58 lbs

Andrea M. Brodie, DVM · Accepted Answer

One of the medical indications for spaying is indeed idiopathic seizures. Sexual hormones do have an impact on brain cell excitability and seizures. Estrogen is consistently found to increase susceptibility to seizures. So spaying is recommended.

My dog has seizures. Can spaying help reduce their frequency?

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