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My pet's mouth sore isn't healing. How long for amoxicillin to work?

Updated On September 23rd, 2025

Pet's info: Dog | German Shepherd | Male | 1 year and 3 months old

Is amoxicillin potassium clavulanate 625mg is good to treat and heal mouth sores in the mouth and beneath the tongue ? How many days course generally vet prescribed ? As my vet prescribed 10 day course twice daily so today is 6th day and I have seen very slightly change that ulcer in mouth has taken little pink color from white but small mass is still there how many days will it take for the small lump to get disappear and in general cases mostly how many days it take to get heal permanently?

2 Answers

Most Helpful Answer

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Answered By Dr. Leigh, DVM

Veterinarian

Published on March 22nd, 2017

If the mouth sore is caused by a bacteria than the antibiotics should help to heal the sores. Typically, antibiotics are used for 10 to 14 days. If the ulcer is still persisting after the 10 days than call your vet and give him an update. If it is not caused by a bacterial infection than the antibiotics will probably not help. Your vet could get a biopsy if needed to determine the exact cause of the lesion.

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Other Answers

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    Answered By Destini R. Holloway, DVM

    Veterinarian

    Published on March 20th, 2017

    Amoxicillin has moderate penetration in the mouth cavity, so it can be used to treat mouth sores in pets. However Clindamycin has the best absorption in the mouth and therefore is typically used as the first line of defense, as long as the pet isn't hypersensitive to it. There is no cause for concern for damage to either the liver or kidney. The ulcer changing from white to pink color is a sign that its healing. Healing occurs within 7-10 days in most cases. If it doesn't heal properly within that time frame then consult with your vet about either extending the course of treatment or trying a different antibiotic (i.e. clindamyicn). Best wishes with Danny and his recovery.

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