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My dog has lymphoma. What's the best treatment: chemo or prednisone?

Updated On September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Female | spayed | 8 years and 2 months old | 79 lbs

My 8 yr old lab was diagnosed with lymphoma what is your advice on treatment? Chemo or prednisone ?

1 Answer

Most Helpful Answer

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Answered By Lauren Jones VMD

Veterinarian

Published on March 21st, 2017

I'm sorry to hear that Daisy received this diagnosis. There are certainly risks and benefits to both options with respect to side effects, life span and cost. Side effects of prednisone in the short term can cause excessive drinking and urination. Some animals with underlying heart disease can go into congestive heart failure and other animals can develop diabetes as a result of the high doses of corticosteroids given in these situations. Around 40% of dogs can achieve remission for 4-6 weeks with prednisone alone, but this is certainly based upon an individual's response to medication and if any metastatic (spread) of disease is present. Obviously, this treatment is much less expensive, but a much shorter survival time is expected. Daisy's chemotherapy protocol is based on whether she has B cell or T cell lymphoma and if any metastatic disease is present. As a generalized statement, lymphoma responds to chemotherapy better than most cancers. Oncologists strive to administer chemotherapeutic drugs at doses that will kill cancerous cells while avoiding as many side effects as possible. The side effects possible vary with different chemotherapeutic drugs. In short, there is no right or wrong choice. You need to evaluate both options to determine your comfort level. If you haven't already done so, consider a consultation with a veterinary oncologist for more information. I hope this helps!

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