Can I safely combine different flea and tick treatments for my pet?

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Can I combine flea and tick treatments? For example, using topical and oral tick medications at the same time?

Tomasz Wnuk · Accepted Answer

The short answer is...it is not recommended in most situations. Combining different medications may increase the risk of negative side effects, adverse reactions or can lead to an overdose situation which could put your pet's life at risk. Due to the variety of [different products](https://www.petcoach.co/article/should-you-use-a-prescription-flea-and-tick-preventive) available on the veterinary market today, pet owners are encouraged to discuss the [best preventative option](https://www.petcoach.co/article/whats-the-difference-between-oral-and-topical-flea-and-tick-preve) for their individual pet with their veterinarian. If a pet has[ fleas](https://www.petcoach.co/article/fleas-life-cycle-anatomy-disease-transmission), most pet owners want to find the fastest treatment option available. In these cases, Capstar ([nitenpyram](https://www.petcoach.co/pet-medication/nitenpyram)) is an oral flea medication available over the counter for dogs and cats that starts treating fleas in 30 minutes and kills 90 percent of adult fleas on a pet within four hours. While Capstar dosing can continue as frequently as every day, topical flea and tick preventatives can be used in conjunction with this oral medication to provide longer lasting treatment and prevention. Oral [flea and tick preventives](https://www.petco.com/shop/en/petcostore/category/dog/dog-and-puppy-flea-and-tick) available for dogs with a prescription from your veterinarian are Credelio, Nexgard, Simparica, and Bravecto. Products that are available with a prescription from your veterinarian for flea treatment include Comfortis or Trifexis. These products also begin to kill fleas quickly and provide ongoing prevention, and do not usually require the concurrent use of a topical medication. If a topical [flea preventative fails](https://www.petcoach.co/article/6-reasons-your-flea-prevention-isnt-working), most oral products can be safely used concurrently. ### Capstar is a trademark of Elanco or its affiliates.

Can I safely combine different flea and tick treatments for my pet?

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