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Can I give my 50-pound dog horse SMZ? What's the right dosage?

Updated On September 23rd, 2025

What is the dosage for a 50# dog? We keep smz for our horses

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Answered By Jessica Desrosiers

Veterinary Technician

Published on January 10th, 2015

The average dosage of SMZ-TMP for dogs is about 13mg per pound given once daily. For a 50 pound dog this would be about 650mg daily. However, if you need to give a medication such as SMZ to your dog it is best to contact your local veterinarian for the correct dosage and usage information as this dosage can vary depending on your dog's personal needs or illness. Antibiotics should only be given under direct veterinary supervision as the antibiotics you have on hand may not be the correct dosage or even type for your dog's current condition. Giving a medication in the wrong dosage or frequency may make the illness worse or cause side effects that are detrimental to your dog.

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