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My dog has high protein in her urine. What causes it and how to treat?

Updated On September 23rd, 2025

Please help my dog has too much protein in her urine. We have put her on science diet food for her kidneys but the result r still high she is only 5

1 Answer

Most Helpful Answer

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Answered By Christie Long, DVM

Veterinarian, Certified Veterinary Acupuncturist

Published on October 16th, 2015

Hi, thanks for writing. Sounds like your dog has a protein-losing nephropathy, which we abbreviate PLE. Food alone doesn't do much, unfortunately, and we really have to treat the underlying cause. There are a huge list of things that can cause a PLE. Many breeds of dogs can pass this on genetically - Bernese mountain dogs, beagles, soft-coated wheaten terriers, cocker spaniels to name a few. All of these dogs have a specific kind of dysfunction in their kidney that causes the protein loss, and the only way you can tell which one it is is by doing a biopsy of the kidney. Infectious diseases can cause PLE's too - chronic bacterial infections, fungal disease, tick borne disease (like Lyme disease). Cancer can cause it, as well as drugs like steroids and other diseases like diabetes. What I'm trying to get at is that protein in the urine isn't a diagnosis - it's a sign of another disease. In order to treat it you have to figure out what's causing it. If you want to do a consult I'd be happy to talk more with you about this - it's a complicated problem.

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